Friday, July 31, 2020

College Application Essay Format

College Application Essay Format In academic work, your paragraphs are likely to be a bit longer than most of the ones you see in this blog post. On average, there are usually 100 to 200 words in a paragraph. So if you’d like a guesstimate, you can assume that a 1,000-word essay will have between five and ten paragraphs. or secondary sources) to back up the points you want to present. In most cases, an essay like this will also require you to address main points which may oppose your stand on an issue or topic. We have one narrative essay template in EssayJack, Short Narrative, which you can use to practice getting the flow of a good story. If you are on a personal connection, like at home, you can run an anti-virus scan on your device to make sure it is not infected with malware. So theoretically, you can have a paragraph consisting of one word plus punctuation marks. 1,000 words in direct speech would therefore mean you’d write way more than the five or ten paragraphs our initial guideline suggested. Always avoid the least reliable sources, such as blogs or random articles. As a short essay is determined by its length, it should have maximum of 3 body paragraphs. Page no. depends on the spacing between the lines. A short or brief essay is defined by its length and the depth of ideas which are presented in it. There is a limited word count for this type of an essay, so you need to make sure that you put in right words and ideas. Before moving on to know about an essay of short length, let’s learn a bit about “what is an essay? Keep your sentences short and should explain the meaning perfectly. Along with linking words, your focus should be on vocabulary as well. Make sure that you are using correct proverbs, words etc. in your essay. For direct speech, one for every time you change speaker . It’s a lot less cumbersome to skip a mention of the speaker than to add “said Mary” and “John said” after every direct quote. Each paragraph can represent one point but, there should be a flow between those paragraphs. The introductory paragraph must introduce the idea which will be discussed in the essay. Your introduction should build up the interest of the audience, and it should be clear that what is the topic. The main parts that build up a short essay are introduction, body and a conclusion. Introduction and conclusion should not be more than one paragraph, and the body can be about 3 paragraphs. The essay needs to answer the question or, you can say the topic assigned to you. A short essay should be of approximately words and 1 page to 2 pages. If your information is from reliable sources, your chances of getting excellence will get high. Try to go for the websites that end with .edu or .gov. For example, if you are writing on any journalism topic, then go for BBC or other well-known news websites. I look forward to your feedback and continued support. You have a limit over the word count, therefore, using excessively long speech doesn’t make a sense in a short essay.

Thursday, June 18, 2020

Alzheimers Disease - Progressive Neurodegenerative Disease - Free Essay Example

Introduction Its very common and accounts for 60-80 percent of the dementia cases in the united states. Alzheimers is caused by the buildup of a type of plaque in the brain. It interrupts the electrical signals between neurons that normally direct thoughts and memories in the brain. The result is that the person slowly becomes more and more forgetful. A certain amount of forgetfulness is normal with aging but those suffering from Alzheimers disease develop far more disrupted thinking patterns. People suffering from AD eventually lose the ability to recognize familiar people, even family memories. Sometimes, in late stages, their personalities change also, they become paranoid, and they become completely unable to take care of themselves. There is no cure for the disease and the medications available only treat the symptoms and show no promise in slowing the progression of this disease. Previous studies on aspirin and heart health showed a link between aspirin and Alzheimers disease. These studies showed that regular use of NSAIDs, including aspirin showed the users had a 20% lesser chance of developing Alzheimers disease. Doctors and scientists do not know what exactly causes this disease but they have a pretty good idea. The major issue seems to be a minuscule brain protein fragment called beta-amyloid. This beta amyloid is a small piece of a larger protein called amyloid precursor protein (APP). When APP is turned on to do its normal job, it is cut by other proteins into smaller sections that stay inside and outside cells. when this protein is cut, one of those cut pieces formed is beta-amyloid and when that forms into clumps it produces those dangerous amyloid plaques. Dr. Kalipada Pahan who is a professor of neurological sciences at Rush University, gather a team of professors and decided to use this connection between aspirin and Alzheimers diseases to carry out experiments that would show in depth how exactly did the aspirin help with the disease. Dr. Pahan felt that developing drugs that can reduce the amount of beta amyloid, which can in turn form amyloid plaques, is an important area of resea rch because these plaques are one of the pathological indications of this disease. Dr.Pahan and his team developed an experiment that entailed giving aspirin to mice with a mouse version of AD. He and his team genetically modified mice so that they had symptoms that resembled AD and so that they resembled the brain pathology of Alzheimers patients. They also measured the amount of beta-amyloid that built up in the brains of the mice. Dr.Pahan and his team gave aspirin to the mice by mouth for about a month then took note of how much of amyloid plaque built up in the parts of the brain affected most by Alzheimers disease. The study revealed that aspirin stimulates the waste-clearing lysosomes and reduces pathological plaque in mice. Lysosomes are supposed to be the waste deposit center for the cell. They are the bad protein clean up system inside all animals that consist of cells that capture and internalize bad proteins. The lysosomes are the components of these cells that break down the captured proteins. In the brain these lysosomes apparently lack the ability to properly do their jobs in patients of AD. Scientist assumed that these lysosomes were degrading the beta amyloid protein before it could turn into amyloid plaques but thats not the case. These lysosomes that accumulate around the plaques are uncommonly embellished wi th beta secretase. This beta secretase is the enzyme that starts the production of the beta amyloid. These nonfunctional lysosomes cannot break down the beta amyloid so the ability to increase lysosomal clearance in the brain of AD patients has come about as a very promising strategy in slowing the progression of this disease. The experiment also revealed that aspirin intake upregulated a protein called TFEB. TFEB is transcription factor EB and it is known as a key player in lysosomal biogenesis. A transcription factor is a protein that will bind to specific parts of the DNA as either and inducer or a repressor. Transcription factor EB exhibited activity that shows how its able to bond to the promoter region of autophagy genes and activate autophagosome biogenesis. The over expression of TFEB has been shown to provide positive effects in many mouse models more recently the mouse models of the most familiar genetic explanation of liver disease, the ? ±1-antitrypsin deficiency. TFEB upregulation has also been proven to reduce obesity and metabolic syndrome therefore upregulation of intracellular removal by TFEB has also been proven to be beneficial in multiple mice models. Aspirin is a commonly used medication and thru multiple test it was shown to upregulate TFEB and boost lysosomal biogenesis in brain cells. The aspirin was also shown to bring about the activation of PPAR? ± encourage the transcription of TFEB in a PPAR? ± fashion. PPAR? ± stands for peroxisome prolif erator-activated receptor ? ±. What PPAR? ± does is when activated, it functions as a ligand-activated TF to regulate the many biological processes that occur within the body. In the 1960s scientist treated a model of rats with Clofibrate, which is now used for controlling the high cholesterol level in the blood, and the outcome of this is that it showed for the first time that the Clofibrate induced peroxisome proliferation in the rats. A while after PPAR? ± was shown to control and help regulate the expression of genes involved in regulating homeostasis, immune response, cell growth and differentiation and many other functions. In the mice model for AD, PPAR? ± was proven to master regulators of metabolism which is why it is important when it comes to developing medications and treatments that can help slow the progression of Alzheimers in the elderly. Materials and Methods 7 month old male and female mice were given low dose aspirin (2 mg/kg body weight/ day) for 30days. The Mice were anesthetized with ketamine-xylazine then half of the brain from each mouse was dissected so assays can be performed on them. the brains were incubated in 4% paraformaldehyde then they were incubated in 30% sucrose overnight at 4 degrees Celsius. They were then rinsed with cold ethanol then rinsed with phosphatebuffered saline 3 times. The brains were then incubated then inspected under a fluorescent microscope. To observe the DNA-binding activity of PPAR? ±, it was analyzed using a non-radioactive electrophoretic mobility shift assay. The cells were then washed with phosphatebuffered saline the placed into tubes to go into the centrifuge for 5 minutes. They then took the supernatant and placed it in lysis buffer and ran it thru the centrifuge again. After that they took the supernatant put it in a high salt buffer then placed it in the centrifuge for 15 minutes. They then placed it on a polyacrylamide gel for 2 hours then observed it under the Odyssey Infrared Imaging System. Results It was proven that aspirin was able to increase the lysosomes in the brain and this was further proven by using an Electron microscopy which showed the different stages of autophagic vesicles in aspirin-treated astrocytes. They then wanted to know if aspirin could alter TFEB. TFEB was increased after the first treatment with the aspirin. The western blot showed larger quantities of TFEB with the different doses of aspirin. The largest increase in TFEB was shown 12 hours after the aspirin treatment was done. Majority of the TFEB activity was found in the cells surrounding the nucleus in cells compared to the control group. these results of this study showed that the aspirin activated lysosomal biogenesis by upregulating the TFEB regulator. They discovered that when PPAR? ± is present, the aspirin binds to it and triggers a domino effect causing increased nerve cell interactions in the hippocampus which is a place in the brain were memories are formed. The mice were showed to have an increased ability to learn their way thru mazes after the aspirin was administered. Even though this study has shown positives effects from the use of aspirin on the brain of the genetically modified mice, aspirin should not be used as a way to treat AD because all of the side effects are not known and its not specifically proven to help with AD. For aspirin to even help with lysosomal production the receptor for PPAR? ± need to be present in the patient. If it is not there in great numbers then the patie nt wont benefit from the aspirin at all.

Monday, May 18, 2020

50 Great Topics for a Process Analysis Essay

If youve ever read an instruction manual or written a set of directions, then you are probably familiar with process analysis writing. This form of composition is often used in the field of technical writing to explain the process of a complex system logically and objectively. Because the material covered in process analyses can be quite complicated, this type of writing tends to be detailed and long. What Is Process Analysis Writing? Process analysis  writing involves a comprehensive set of instructions that explains a process from beginning to end. To successfully write a process analysis essay, writers must critically analyze each step of the process they have chosen to describe and determine the most reasonable way of delivering information before writing. Expertise is required when explaining a process with this level of detail and this can be obtained through firsthand experience or thorough research. The topic of a process analysis essay needs to be as specific as possible and it is crucial that the tone of the essay be clear and straightforward. A writers main goal when crafting a process analysis essay should be to make a process easy to follow. Below is a set of tips that will help you achieve this. Tips for Writing a Process Analysis Essay When writing an essay or speech through process analysis, keep these tips in mind:Include all steps and arrange them in chronological order.Explain why each step is necessary and include warnings when appropriate.Define any terms that may be unfamiliar to readers.Offer clear descriptions ​of any required tools or materials.Give your readers a way to measure the success of the finished process. 50  Process Analysis Essay Topics Writers will have an easier time writing process analysis essays and following the above guidelines for topics they know well. To begin, choose a subject that you enjoy writing about and know that you can explain well. These prompts offer potential process analysis essay topics to get you started. How to mow your lawnHow to win a game of Texas hold em pokerHow to lose weight without losing your mindHow to find the perfect roommateHow to get rid of a roommate—without committing a crimeHow to achieve academic success in collegeHow to pitch a knuckleball in baseballHow to plan the perfect partyHow to survive a night of babysittingHow to pitch a tent in the rainHow to housebreak your dogHow to kick a bad habitHow to overcome insomniaHow to stay sober on a Saturday nightHow to rent your first apartmentHow to avoid a nervous breakdown during examsHow to enjoy the weekend for less than $20How to make the perfect browniesHow to keep resolve arguments with your spouseHow to bathe a catHow to get what you want through complainingHow to survive a recessionHow to toilet train a babyHow to gain self-confidenceHow to use Twitter sensibly and effectivelyHow to wash a sweaterHow to remove stubborn stainsHow to build successful relationships with instructorsHow to give yourself a haircu tHow to plan the perfect class scheduleHow to apply the Heimlich maneuverHow to end a relationshipHow to make a flaky pie crustHow to take the best photographs with a smartphone cameraHow to quit smokingHow to get around without a carHow to make the perfect cup of coffee or teaHow to maintain an eco-friendly and affordable lifestyleHow to build a great sandcastleHow to edit a videoHow to build and maintain a stable friendshipHow to insert contact lensesHow to write a great examHow to teach responsibility to a childHow to groom your dogHow ice cream is madeHow a cell phone takes picturesHow a magician saws a woman in halfHow solar panels workHow to choose a major in college

Wednesday, May 6, 2020

Bernie Madoff Case Study Essay example - 1431 Words

Bernie Madoff Case Study Tanya Seyfried GFN61090033-ACFA12 January 19, 2013 Bernie Madoff was a successful gentleman whose financial career spanned almost 50 years. Some of his achievements include serving as the chairman of the board of the NASDAQ stock exchange; a member of the Board of Directors on the Security Industry Association; and a former National Treasurer of the American Jewish Congress. (Hirt, Block, Danielsen 2011) His greatest achievement was starting and being the chairman of Bernard L. Madoff Investment Securities LLC in 1960. His investment group gave him wealth and notoriety among the financial elite of New York City and around the entire country. Many trusted him and accepted his†¦show more content†¦In four separate attempts, Markopolos met with officials at the SEC (in 2000 and 2001 with the Boston, Massachusetts, SEC office and again in 2005 and 2007 at the New York City SEC office) to convey and expose the truth about Madoff. However, these statements fell on deaf ears. Finally in 2008, the Federal Bur eau of Investigation (FBI) received a criminal complaint filed by the Manhattan States which said that he (Madoff) confessed to his two sons, who were both employed at his firm--Bernard L. Madoff Investment Securities LLC--that he had been running a giant Ponzi scheme. (Wall Street Journal 2012) This led to the arrest of Madoff, who was charged with criminal securities fraud. In the three months that followed, Madoff’: had his investment firm liquidated; was banned for life by the SEC from practicing in the investment industry; gave up the rights to his investment firm, artwork, and event tickets; and pled guilty to 11 criminal charges, including securities fraud, wire fraud, mail fraud, money laundering, and making a false filing with the SEC. The judge ordered him to jail, pending sentencing and revoked his bail. (Wall Street Journal 2012) Bernie Madoff today sits in a federal prison in North Carolina serving his 150-year sentence. Although justice has been partly done , many of those who invested in his ponzi scheme haveShow MoreRelatedBernie Madoff Case Study3354 Words   |  14 PagesCase Study: Bernie Madoff Eric Ranzinger Organizational Behavior – OL 500 Jascia Redwine Abstract Bernie Madoff was one of the top dogs on Wall Street for over 20 years. He managed tens of billions of dollars in client’s funds. His firm was one of the most consistent with profitable returns. When most others were reporting losses during the recession, his firm was consistently reporting net gains. Many celebrities even entrusted their money with Madoff because he was such a reputable nameRead MoreBernie Madoff Case Study3401 Words   |  14 PagesOperated through a complex, cryptic structure Bernie Madoff, CEO of Bernie L. Madoff Investment Securities (BMIS), perpetuated the most embellished Ponzi scheme the world has ever seen. The basis of the securities fraud that took place approximately between 1991 – 2008 was influenced by Bernie Madoff’s reliance upon an unqualified staff, outdated software, organizational seclusion, a personal halo effect, and weaknesses in the regulating body. Madoff had the confidence of the public, yet to pullRead MoreBernie Madof f Case Study4737 Words   |  19 PagesThe Fraud of the Century: The Case of Bernard Madoff The fraud perpetrated by Bernard Madoff which was discovered in December, 2008 is based upon a Ponzi scheme. Madoff took money from new investors to pay earnings for existing customers. The greater the payout to retiring and withdrawing customer, the more revenue or clients he would need to start and â€Å"investment relationship† with Madoff. 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In summary the scheme occurred for many reasons that I will some up into 3 points; A lack in competency by regulatory agencies, a lack of regulation, and finally a breach in ethics by Bernie Madoff himself. To explain further, the regulatory agencies like the lawyers and SEC are supposed to prevent schemes such as this one from happening but because they lacked the skills to correctly

Is there Truth in Art Essay Example For Students

Is there Truth in Art? Essay Art is all things made by man which are collectively perceived to have creative value, including but not limited to: elegant mathematical proofs, interesting cosmological models, paintings, and great literary works. All of these â€Å"frivolous† activities by their nature lead us closer to truth. Plato will of course disagree with this claiming that by further skewing the shadows on the walls of his cave we are obviously further from truth. However, isn’t refocusing our lens the best way to capture more of the picture. Art lets us shift our perception and communicate it to our species. Paintings, which are held of value, did not get to that position by mistake. It was a conscious decision of our species to consider it art. The perspective the artist provides is one that is possibly different from our own. Looking at the night sky everyone sees something different, but we all have Van Gough’s Starry Night to interpret together. This offers us a liberating new glance towards beliefs we may already hold. While it can be argued that culture affects our perception too heavily to be open to new ideas portrayed in art, through expression of a new way in approach those who wish to see beyond what their rose coloured glasses show them, have an opportunity to see. In an epistemological pursuit for knowledge, language is a way to express new paradigms and reform old ones. The central problem is without a universal way of expression it is difficult to transmit knowledge across our diverse peoples. Art like the use of metaphor or an elegant mathematical, allows us to understand the ideas and move past the problems of language. For example, almost all representations of the inner working of atoms have been given through metaphor. Thompson’s raisin bun model to describe the way electrons and protons were arranged permitted Bohr to prove him wrong and devise a new method. Similarly, in the case of the epicycles, this perfectly crafted idea was destroyed by Copernicus and Galileo only after it had been understood. An iconoclast cannot fulfil his duty without knowledge of the traditional knowledge he is destroying. These artistic representations give us a way into both seeing and understand the current in order to create the future. As a new way of seeing and a way into understanding, ideas with artistic appeal give us a collective view of the world that no other species, which we know of, is privileged with. We are given the gift of not only experiencing the world around us, but trying to comprehend it.

Thursday, April 16, 2020

Academic Topics For Presentation

Academic Topics For PresentationWhen presenting information to your audience in a public or college setting, there are numerous academic topics that you will want to consider. Each one of these topics requires preparation in advance in order to be effective in your presentation. Here are just a few examples of what to include in each of the academic topics for presentation.First, the topic should include the actual content of the presentation. This includes how many people will be attending the event, the intended length of the presentation, and the possible technical specifications on the equipment being used in the presentation. Other considerations can include the date and time, venue, location, or the location of the audience.Next, the presentation must be written in such a way that it can be read quickly and easily, and there is no confusion about which paper should be handed out at the end of the presentation. There should be no hocus-pocus associated with the paper, and the in formation presented should flow easily from one point to another. For example, if an event is held at night, there should be no confusion about which paper should be handed out at the end of the evening.The size of the audience is a key consideration for many presentations. If the presentation is intended for a large audience, the size of the paper should be minimal. However, if the audience is much smaller, there should be more papers to be distributed to the audience at the end of the presentation. This can result in more work for the presenter.Finally, when choosing the type of paper to use in the presentation, the focus of the paper should be clearly identified. The paper should be used for the purpose of instruction and not just as a method of generating interest. Sometimes this means that there is little room for ideas, but the purpose of the presentation needs to be clear. For example, a PowerPoint presentation should always discuss the content of the data for the data presen tation.With the many different forms of presentation options available, it is important to know what form is best for the intended audience. The most popular way to present information is in the written form, although many others are used as well. For example, people love to see video presentations, but many have difficulty reading graphics, and some prefer to watch videos instead of reading lengthy documents.The purpose of the presentation style is determined by the intended audience. This includes the specific audience, audience goals, and the format that can be used. For example, if the audience does not have time to review the material, they need to be able to quickly understand the material that is being presented. On the other hand, if the audience has a large task to accomplish, then it is important to set up the required steps for completing the task, and include the time frame in the presentation.When you are presenting information in a presentation, there are many academic topics for presentation. Each one requires preparation in advance in order to be effective in your presentation. Here are just a few examples of what to include in each of the academic topics for presentation.

Wednesday, April 8, 2020

NJHS Essay - Important Skills You Need to Know

NJHS Essay - Important Skills You Need to KnowThe NJHS Essay requires a solid understanding of the subject. These types of exams are used for assessing the study skills and progress of students in the NJHS. They make sure that students understand the curriculum to a very high level and they can also help in improving their working skills as well.As per the NJHS, the subjects included in the syllabus are English, Mathematics, Reading, Science, Social Studies, and History. Students are also encouraged to understand how the general education is achieved by visiting the NJHS website. There, students can learn more about how the NJHS system works. If students do not understand the curriculum fully, the NJHS will help them understand it.One of the most basic subjects which students are required to cover in the NJHS Essay is General Science. As the curriculum is basically very liberal, students are required to understand all the concepts related to the General Science subjects.The General S cience subjects include biology, chemistry, geography, math, physics, astronomy, and biology. Students will also be required to understand the subjects such as English Literature, History, English, Civil Engineering, Biochemistry, Physics, and Physical Education. There are specific areas that students need to know about. One of these areas includes botany, physical education, marine science, and physical education.Some other general subjects that students need to understand include general education for the NJHS Oral exam. In this, students will be tested on their knowledge of the Literature, reading, composition, mathematics, social studies, social sciences, and math. As the English essay requires students to use the English language, the NJHS Essay demands that students write a good essay. In order to write good essays, students will be provided with sample essays and writings to read and analyze.Students are required to answer the following questions in English writing. These que stions will determine the difficulty level of the essay. These questions are: Which is the goal of the essay? What can the essay be used for?The NJHS Essay requires a student to first write an essay on the topic, then edit it. The student must then submit the essay to the NJHS officials.